Streaming for 12-24+ hours can be difficult on the body. The chair may become uncomfy and so much more including hand cramping and the desk hurting your wrist but there is a solution for that.
Upper Echelon Products has all kinds of cushions to make you comfy no matter what it is.
They have foot rest, seat cushions back pillows that goes into chairs, mouse pad with cushion, desk mat that is RGB which is cool.
This company is all about being comfy because they have so much more than that like pillows, blankets, and other household items.